Trophies:
Bronze trophies
Extermination – Kill 50 aliens.
Annihilation – Kill 100 aliens.
Nuclear Devastation – Kill 250 aliens.
On the Noggin’ – Kill 30 aliens with headshots.
Hippy-Stomper – Foot stomp 12 aliens.
Judge, Jury, Executioner – Execute 20 aliens.
Trapper – Kill 10 aliens with Trip Mines.
Freeze Well! – Kill 15 frozen aliens.
Road Rage – Kill 15 aliens with the monster truck.
Fork the Pork – Kill 6 aliens with the forklift.
Dead Useful – Kill 10 aliens with environmental explosives.
Tosser…in the Literal Sense – Kill 10 aliens with tossed objects.
Duke Angry, Duke SmasH! – Kill 15 aliens with melee attacks while on steroids.
Noms – Eat 10 pieces of food in SP.
Natural Disaster 3x – Kill 3 aliens at once.
Full Body Tourettes – Get knocked down 10 times.
Turd Burglar – Find and steal a piece of poo.
I Need a Towel – Get hit by 10 Pregnator bombs.
Baron von Nukem – Shoot down 20 alien fighters.
Bucket Head – Find all 3 helmets in the SP campaign.
Party Animal – Drink all of the beers in the strip club.
Pescaphobe – Kill all of the catfish in the underwater level.
Drawrings – Doodle something on the whiteboard in SP.
I Need a Date – Look at every page of a calender in SP.
Sticky Bomb Like You! – Put a Trip Mine on a live alien.
Big Guns, Big Ships – Blow up 5 enemy Gunships or Dropships.
Flagon of Chuckles – Drink a beer in SP.
Juiced – Take steroids in SP.
He’s Got a Hologram! – Use a Holoduke in SP.
Substance Abuser – Drink beer while on steroids or vice-versa in SP.
Sunday, Black Sunday – Shoot down the blimp above the stadium.
Nobody Likes a Whiner – Knock out the talent at the talk show.
Lots of Whacking – Win a game of Alien Abortion in the strip club.
Companion Barrel – Unlock the secret closet at the end of the Forkstop.
One-Eyed Freak – Defeat the Cycloid.
Pit Champion – Defeat the Battlelord in Las Vegas.
Piece of Cake – Complete the SP campaign on Easy Difficulty.
Special Thanks – Watch the credits all the way through.
Silver trophies
Call Waiting – Listen to all phone messages.
Air-Duke – Win air hockey with a score of 7-0 in the strip club.
Balls of Steel – Earn a 1,000,000 pinball score in SP.
I Am All That Is Man – Discover all ego cap rewards.
Gunslinger – Carry the gold pistol through the whole SP campaign.
Not Bad for a Human – Defeat the Alien Queen.
A Good Dam Fight – Defeat the Battlelord on the Hoover Dam.
Octacide – Defeat the Octaking.
Beating the One-Eyed Worm – Defeat the Leech.
Let’s Rock – Complete the SP campaign on Normal Difficulty.
Gold trophies
Come Get Some – Complete the SP campaign on Hard Difficulty.
Damn, I’m Good – Complete the SP campaign on Insane Difficulty.
Platinum trophy
Savior of the Universe – Earn all Bronze, Silver, and Gold trophies